Boosting Blood Health: The Role of Tender Coconut Water in Leukocyte and Thrombocyte Modulation in Rats

Background and Objective: Tender coconut water (TCW) is a natural beverage rich in bioactive compounds, known for its potential health benefits, including immune modulation and blood health improvement. The TCW from the Malayan green dwarf hybrid was administered in varying doses to assess its impact on blood cell parameters. This study explores the effects of tender coconut water on leukocyte and thrombocyte modulation in Wistar rats, highlighting its potential benefits for immune function and blood health. Materials and Methods: Forty Wistar rats were divided into four groups: Group A (control) received no treatment, while Groups B, C and D were treated with 10, 20 and 30 mL/kg of TCW, respectively. Blood samples were analyzed using a hematology analyzer and statistical evaluation was performed using SPSS version 26. Results: The results showed a significant increase in total white blood cell counts, including lymphocytes, eosinophils, basophils and platelets in the treated groups. A significant decrease in neutrophil counts was also observed (p<0.05). Notably, the group that received 20 mL/kg of TCW exhibited the highest platelet count, surpassing the effects observed at the 30 mL/kg dose. Conclusion: This study suggests that tender coconut water, particularly at a dose of 20 mL/kg, may have immunomodulatory and hemostatic effects, making it a promising natural supplement for enhancing immune function and blood health in Wistar rats. Further research is warranted to explore its potential applications in clinical settings.