Hypolipidaemic Effects of Ethanol Leaf Extract of Eucalyptus camadulensis in Wistar Rats

Background and Objective: Plants are a significant source of medicinal compounds that play a crucial role in global health and serve as an important potential source of treatments. Medicinal plants which are widely used across various health systems, serve not only to treat illnesses but also to maintain overall health. This research is aimed at investigating the hypolidaemic effects of ethanol leaf extract of Eucalyptus camaldulensis in Wistar rats. Materials and Methods: The study involved 40 rats divided into six groups, each given different doses of a plant extract. Biochemical analysis was performed using standard laboratory techniques and significant changes were considered acceptable at a p<0.05 level. Results: Administration of the extract resulted in no significant changes in TC, TG, LDL and VLDL concentrations in all experimental groups when compared to the control group. However, there was a significant increase (p<0.05) in HDL at 150 mg/kg (365.00±46.10) and 450 mg/kg (390.00±75.06). Conclusion: The ethanol leaf extract of Eucalyptus camaldulensis, particularly at doses of 150 and 450 mg/kg, significantly increased HDL levels in the Wistar rats. This suggests its potential as a rapeutichypolidaemic agent which may be responsible for reducing cardiovascular disease risk.