Research Article | Open Access
Volume 16 | Issue 1 | https://doi.org/10.3923/ajbs.2023.10.17

Monitoring of Low-Dose Effects of Bisphenol a on Superoxide Dismutase and Catalase Level in Female Rats

    Chinenye E. Oguazu

    Department of Applied Biochemistry, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Nigeria

    Ezeonu Francis Chukwuemeka

    Department of Applied Biochemistry, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Nigeria

    Enemali Micheal Okechukwu

    Department of Applied Biochemistry, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Nigeria

    Dike Chijioke Charles

    Department of Human Biochemistry, College of Basic Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria

    Ubaoji Kingsley Ikechukwu

    Department of Applied Biochemistry, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Nigeria


Received
20 Jul, 2022		 Accepted
05 Sep, 2022		 Published
31 Mar, 2023

Background and Objective: Inflammatory diseases are becoming increasingly prevalent worldwide, Exposure to environmental pollutants such as BPA could be one of the risk factors responsible for the development of such diseases. This study investigated the relationships between the serum levels of two endogenous antioxidants Enzyme and Bisphenol A concentrations. Materials and Methods: The study groups were divided into eleven healthy experimental animals. Serum Superoxide Dismutase (SOD) and Catalase (antioxidant enzymes), profiles were analyzed by spectrophotometric methods. Results: Serum Superoxide Dismutase (SOD) and Catalase (CAT) levels were significantly decreased in treated groups compared with control (p<0.05). Conclusion: This study demonstrated that the dose of BPA not only increases the free radical formation but also decreases its ability to detoxify ROS.

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APA-7 Style
Oguazu, C.E., Chukwuemeka, E.F., Okechukwu, E.M., Charles, D.C., Ikechukwu, U.K. (2023). Monitoring of Low-Dose Effects of Bisphenol a on Superoxide Dismutase and Catalase Level in Female Rats. Asian Journal of Biological Sciences, 16(1), 10-17. https://doi.org/10.3923/ajbs.2023.10.17

ACS Style
Oguazu, C.E.; Chukwuemeka, E.F.; Okechukwu, E.M.; Charles, D.C.; Ikechukwu, U.K. Monitoring of Low-Dose Effects of Bisphenol a on Superoxide Dismutase and Catalase Level in Female Rats. Asian J. Biol. Sci 2023, 16, 10-17. https://doi.org/10.3923/ajbs.2023.10.17

AMA Style
Oguazu CE, Chukwuemeka EF, Okechukwu EM, Charles DC, Ikechukwu UK. Monitoring of Low-Dose Effects of Bisphenol a on Superoxide Dismutase and Catalase Level in Female Rats. Asian Journal of Biological Sciences. 2023; 16(1): 10-17. https://doi.org/10.3923/ajbs.2023.10.17

Chicago/Turabian Style
Oguazu, Chinenye, E., Ezeonu Francis Chukwuemeka, Enemali Micheal Okechukwu, Dike Chijioke Charles, and Ubaoji Kingsley Ikechukwu. 2023. "Monitoring of Low-Dose Effects of Bisphenol a on Superoxide Dismutase and Catalase Level in Female Rats" Asian Journal of Biological Sciences 16, no. 1: 10-17. https://doi.org/10.3923/ajbs.2023.10.17

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